The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability

Diallyl trisulfide (DATS), a polysulfide constituent found in garlic oil, is capable of the release of hydrogen sulfide (H(2)S). H(2)S is a known cardioprotective agent that protects the heart via antioxidant, antiapoptotic, anti-inflammatory, and mitochondrial actions. Here, we investigated DATS as...

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Bibliographic Details
Main Authors: Predmore, Benjamin L., Kondo, Kazuhisa, Bhushan, Shashi, Zlatopolsky, Maxim A., King, Adrienne L., Aragon, Juan Pablo, Grinsfelder, D. Bennett, Condit, Marah E., Lefer, David J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Integrative Cardiovascular Physiology and Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378306/
https://ncbi.nlm.nih.gov/pubmed/22467307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00044.2012
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