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Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer’s disease

Neprilysin (NEP) is the most important Aβ-degrading enzyme. Its expression level decreases with age and inversely correlated with amyloid accumulation, suggesting its correlation with the late-onset of Alzheimer’s disease. Recently, many reports showed that upregulating NEP level is a promising stra...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Chen, Po-Ting, Chen, Zih-ten, Hou, Wen-Chi, Yu, Lung-Chih, Chen, Rita P.-Y.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942833/
https://ncbi.nlm.nih.gov/pubmed/27407064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29760
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