Upregulation of Cisd2 attenuates Alzheimer's‐related neuronal loss in mice

CDGSH iron–sulfur domain‐containing protein 2 (Cisd2), a protein that declines in an age‐dependent manner, mediates lifespan in mammals. Cisd2 deficiency causes accelerated aging and shortened lifespan, whereas persistent expression of Cisd2 promotes longevity in mice. Alzheimer's disease (AD)...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Chen, Yi‐Fan, Chou, Tzu‐Yu, Lin, I‐Hsuan, Chen, Chung‐Guang, Kao, Cheng‐Heng, Huang, Guo‐Jen, Chen, Liang‐Kung, Wang, Pei‐Ning, Lin, Ching‐Po, Tsai, Ting‐Fen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2020
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065100/
https://ncbi.nlm.nih.gov/pubmed/31837018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5374
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