Upregulation of Cisd2 attenuates Alzheimer's‐related neuronal loss in mice

CDGSH iron–sulfur domain‐containing protein 2 (Cisd2), a protein that declines in an age‐dependent manner, mediates lifespan in mammals. Cisd2 deficiency causes accelerated aging and shortened lifespan, whereas persistent expression of Cisd2 promotes longevity in mice. Alzheimer's disease (AD)...

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Bibliographic Details
Published in:J Pathol
Main Authors: Chen, Yi‐Fan, Chou, Tzu‐Yu, Lin, I‐Hsuan, Chen, Chung‐Guang, Kao, Cheng‐Heng, Huang, Guo‐Jen, Chen, Liang‐Kung, Wang, Pei‐Ning, Lin, Ching‐Po, Tsai, Ting‐Fen
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2020
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065100/
https://ncbi.nlm.nih.gov/pubmed/31837018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5374
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