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Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling
Rotavirus infection is associated with childhood progression to type 1 diabetes. Infection by monkey rotavirus RRV accelerates diabetes onset in non-obese diabetic (NOD) mice, which relates to regional lymph node infection and a T helper 1-specific immune response. When stimulated ex vivo with RRV,...
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Publié dans: | Sci Rep |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Nature Publishing Group
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942798/ https://ncbi.nlm.nih.gov/pubmed/27405244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29697 |
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