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Alteration of the Thymic T Cell Repertoire by Rotavirus Infection Is Associated with Delayed Type 1 Diabetes Development in Non-Obese Diabetic Mice

Rotaviruses are implicated as a viral trigger for the acceleration of type 1 diabetes in children. Infection of adult non-obese diabetic (NOD) mice with rotavirus strain RRV accelerates diabetes development, whereas RRV infection in infant NOD mice delays diabetes onset. In this study of infant mice...

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Autors principals: Webster, Nicole L., Zufferey, Christel, Pane, Jessica A., Coulson, Barbara S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598695/
https://ncbi.nlm.nih.gov/pubmed/23554993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059182
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