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Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression

Inflammatory diseases such as sepsis and autoimmune colitis, characterized by an overwhelming activation of the immune system and the counteracting anti-inflammatory response, remain a major health problem in worldwide. Emerging evidence suggests that methane have a protective effect on many animal...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Xu, Li, Na, Shao, Han, Meng, Yan, Wang, Liping, Wu, Qian, Yao, Ying, Li, Jinbao, Bian, Jinjun, Zhang, Yan, Deng, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942692/
https://ncbi.nlm.nih.gov/pubmed/27405597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29359
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