Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis

Parkinson's disease (PD) is a common neurodegenerative disease characterized by selective loss of dopaminergic neurons in the substantia nigra (SN). Neuroinflammation induced by over-activation of microglia leads to the death of dopaminergic neurons in the pathogenesis of PD. Therefore, downreg...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Huang, Bingxu, Liu, Juxiong, Meng, Tianyu, Li, Yuhang, He, Dewei, Ran, Xin, Chen, Guangxin, Guo, Wenjin, Kan, Xingchi, Fu, Shoupeng, Wang, Wei, Liu, Dianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230593/
https://ncbi.nlm.nih.gov/pubmed/30455692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02527
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