Dioscin Improves Pyroptosis in LPS-Induced Mice Mastitis by Activating AMPK/Nrf2 and Inhibiting the NF-κB Signaling Pathway

Dioscin, a natural steroid saponin, has been shown to have anti-inflammatory effects, but its protective mechanism against mastitis is still unknown. NLRP3 inflammasome and pyroptosis play important roles in the pathogenesis of many inflammatory diseases, including mastitis. The purpose of this stud...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ran, Xin, Zhang, Yan, Yang, Yuanxi, Hu, Guiqiu, Liu, Juxiong, Hou, Shuang, Guo, Wenjin, Kan, Xingchi, Fu, Shoupeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790561/
https://ncbi.nlm.nih.gov/pubmed/33488936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8845521
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