MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to regulate the functional outcome of ubiquitylation. Here we report the discovery of a new family of DUBs, which we have named MINDY (motif interacting with Ub-containing novel DUB family). Found in all eukaryotes,...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Abdul Rehman, Syed Arif, Kristariyanto, Yosua Adi, Choi, Soo-Youn, Nkosi, Pedro Junior, Weidlich, Simone, Labib, Karim, Hofmann, Kay, Kulathu, Yogesh
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
Fag:
Short Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942677/
https://ncbi.nlm.nih.gov/pubmed/27292798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.009
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