MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to regulate the functional outcome of ubiquitylation. Here we report the discovery of a new family of DUBs, which we have named MINDY (motif interacting with Ub-containing novel DUB family). Found in all eukaryotes,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Cell
Hauptverfasser: Abdul Rehman, Syed Arif, Kristariyanto, Yosua Adi, Choi, Soo-Youn, Nkosi, Pedro Junior, Weidlich, Simone, Labib, Karim, Hofmann, Kay, Kulathu, Yogesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2016
Schlagworte:
Short Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942677/
https://ncbi.nlm.nih.gov/pubmed/27292798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.009
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge