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Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy
PURPOSE: To measure the hydrodynamic radii of intravitreal anti-VEGF drugs ranibizumab, aflibercept and bevacizumab with μs time-resolved phosphorescence anisotropy. METHODS: Ruthenium-based dye Ru(bpy)(2)(mcbpy − O − Su − ester)(PF(6))(2), whose lifetime of several hundred nanoseconds is comparable...
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Publicado no: | Pharm Res |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942501/ https://ncbi.nlm.nih.gov/pubmed/27225494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-1940-2 |
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