Association of polymorphisms in the regulatory region of the cyclophilin A gene (PPIA) with gene expression and HIV/AIDS disease progression

BACKGROUND: Human cyclophilin A (CypA) encoded by peptidyl prolyl isomerase A gene (PPIA), enhances human immunodeficiency virus type 1 (HIV-1) replication by aiding capsid uncoating. The association of genetic variation in the PPIA regulatory region with susceptibility to HIV-1 infection, disease p...

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Bibliographic Details
Published in:J Acquir Immune Defic Syndr
Main Authors: Madlala, Paradise, Singh, Ravesh, An, Ping, Werner, Lise, Mlisana, Koleka, Abdool Karim, Salim S., Winkler, Cheryl A., Ndung’u, Thumbi
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942341/
https://ncbi.nlm.nih.gov/pubmed/27088296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001028
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