A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease

APOE ε4 is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD) and accounts for 50–65% of late-onset AD. Late-onset AD patients carrying or not carrying APOE ε4 manifest many clinico-pathological distinctions. Thus, we applied a weighted gene co-expression network analysis to i...

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Udgivet i:Front Aging Neurosci
Main Authors: Jiang, Shan, Tang, Ling, Zhao, Na, Yang, Wanling, Qiu, Yu, Chen, Hong-Zhuan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941795/
https://ncbi.nlm.nih.gov/pubmed/27462267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00171
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