Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors

Inhibition of acetylcholinesterase (AChE) using small molecules is still one of the most successful therapeutic strategies in the treatment of Alzheimer’s disease (AD). Previously we reported compound T5369186 with a core of quinolone as a new cholinesterase inhibitor. In the present study, in order...

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Опубликовано в: :PeerJ
Главные авторы: Chen, Yao, Bian, Yaoyao, Sun, Yuan, Kang, Chen, Yu, Sheng, Fu, Tingming, Li, Wei, Pei, Yuqiong, Sun, Haopeng
Формат: Artigo
Язык:Inglês
Опубликовано: PeerJ Inc. 2016
Предметы:
Biochemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941764/
https://ncbi.nlm.nih.gov/pubmed/27441112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2140
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