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Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors

Inhibition of acetylcholinesterase (AChE) using small molecules is still one of the most successful therapeutic strategies in the treatment of Alzheimer’s disease (AD). Previously we reported compound T5369186 with a core of quinolone as a new cholinesterase inhibitor. In the present study, in order...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Chen, Yao, Bian, Yaoyao, Sun, Yuan, Kang, Chen, Yu, Sheng, Fu, Tingming, Li, Wei, Pei, Yuqiong, Sun, Haopeng
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941764/
https://ncbi.nlm.nih.gov/pubmed/27441112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2140
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