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Tumor-associated fibroblasts predominantly come from local and not circulating precursors
Fibroblasts are common cell types in cancer stroma and lay down collagen required for survival and growth of cancer cells. Although some cancer therapy strategies target tumor fibroblasts, their origin remains controversial. Multiple publications suggest circulating mesenchymal precursors as a sourc...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941507/ https://ncbi.nlm.nih.gov/pubmed/27317748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600363113 |
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