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E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors

The mammalian lung is an elaborate branching organ, and it forms following a highly stereotypical morphogenesis program. It is well established that precise control at the transcript level is a key genetic underpinning of lung branching. In comparison, little is known about how regulation at the pro...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Zhang, Yan, Yokoyama, Shigetoshi, Herriges, John C., Zhang, Zhen, Young, Randee E., Verheyden, Jamie M., Sun, Xin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941481/
https://ncbi.nlm.nih.gov/pubmed/27335464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603310113
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