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FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds

Anterior-posterior (A-P) patterning of the vertebrate limb is controlled by sonic hedgehog (SHH) signaling, and the precise restriction of Shh expression to the posterior limb bud is essential for its polarizing effect. Fibroblast growth factor (FGF) signaling, a key control of proximal-distal (P-D)...

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Main Authors: Zhang, Zhen, Verheyden, Jamie M, Hassell, John A., Sun, Xin
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541528/
https://ncbi.nlm.nih.gov/pubmed/19386269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.02.008
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