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FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds

Anterior-posterior (A-P) patterning of the vertebrate limb is controlled by sonic hedgehog (SHH) signaling, and the precise restriction of Shh expression to the posterior limb bud is essential for its polarizing effect. Fibroblast growth factor (FGF) signaling, a key control of proximal-distal (P-D)...

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Autores principales: Zhang, Zhen, Verheyden, Jamie M, Hassell, John A., Sun, Xin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541528/
https://ncbi.nlm.nih.gov/pubmed/19386269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.02.008
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