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Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis
Proper deposition and activation of Aurora B at the centromere is critical for faithful chromosome segregation in mammals. However, the mechanistic basis for abrupt Aurora B kinase activation at the centromere has not yet been fully understood. We demonstrate here that Aurora B-mediated phosphorylat...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941122/ https://ncbi.nlm.nih.gov/pubmed/27389782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12059 |
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