The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation

BACKGROUND: Amyloid-β (Aβ)-stimulated microglial inflammatory responses engage mitogen-activated protein kinase (MAPK) pathways in Alzheimer’s disease (AD). Mixed-lineage kinases (MLKs) regulate upstream MAPK signaling that include p38 MAPK and c-Jun amino-terminal kinase (JNK). However, whether MLK...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Neuroinflammation
Glavni autori: Dong, Weiguo, Embury, Christine M., Lu, Yaman, Whitmire, Sarah M., Dyavarshetty, Bhagyalaxmi, Gelbard, Harris A., Gendelman, Howard E., Kiyota, Tomomi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940949/
https://ncbi.nlm.nih.gov/pubmed/27401058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0646-z
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items