טוען...
The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation
BACKGROUND: Amyloid-β (Aβ)-stimulated microglial inflammatory responses engage mitogen-activated protein kinase (MAPK) pathways in Alzheimer’s disease (AD). Mixed-lineage kinases (MLKs) regulate upstream MAPK signaling that include p38 MAPK and c-Jun amino-terminal kinase (JNK). However, whether MLK...
שמור ב:
| הוצא לאור ב: | J Neuroinflammation |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940949/ https://ncbi.nlm.nih.gov/pubmed/27401058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0646-z |
| תגים: |
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