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The relevance of coagulation factor X protection of adenoviruses in human sera
Intravenous delivery of adenoviruses is the optimal route for many gene therapy applications. Once in the blood, coagulation factor X (FX) binds to the adenovirus capsid and protects the virion from natural antibody and classical complement-mediated neutralisation in mice. However, to date, no studi...
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| Publicado no: | Gene Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940928/ https://ncbi.nlm.nih.gov/pubmed/27014840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.32 |
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