Honokiol sensitizes breast cancer cells to TNF‐α induction of apoptosis by inhibiting Nur77 expression

BACKGROUND AND PURPOSE: The orphan nuclear receptor Nur77 is implicated in the survival and apoptosis of cancer cells. The purpose of this study was to determine whether and how Nur77 serves to mediate the effect of the inflammatory cytokine TNF‐α in cancer cells and to identify and characterize new...

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Udgivet i:Br J Pharmacol
Main Authors: Xie, Lei, Jiang, Fuquan, Zhang, Xindao, Alitongbieke, Gulimiran, Shi, Xinlei, Meng, MinJun, Xu, Yiming, Ren, Anshi, Wang, Jing, Cai, Lijun, Zhou, Yunxia, Xu, Yang, Su, Ying, Liu, Jie, Zeng, Zhiping, Wang, Guanghui, Zhou, Hu, Chen, Quan Cheng, Zhang, Xiao‐kun
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940620/
https://ncbi.nlm.nih.gov/pubmed/26505879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13375
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