Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK

Orphan nuclear receptor Nur77 promotes apoptosis by targeting mitochondria through interaction with Bcl-2, an event that converts Bcl-2 from a survival to killer. However, how the Nur77-Bcl-2 apoptotic pathway is regulated remains largely unknown. In this study, we examined the regulation of the Nur...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Liu, Jie, Wang, Guang-Hui, Duan, Ying-Hui, Dai, Yi, Bao, Yuzhou, Hu, Mengjie, Zhou, Yu-Qi, Li, Mingyu, Jiang, Fuquan, Zhou, Hu, Yao, Xin-Sheng, Zhang, Xiao-Kun
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642512/
https://ncbi.nlm.nih.gov/pubmed/29050237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19227
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