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Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK
Orphan nuclear receptor Nur77 promotes apoptosis by targeting mitochondria through interaction with Bcl-2, an event that converts Bcl-2 from a survival to killer. However, how the Nur77-Bcl-2 apoptotic pathway is regulated remains largely unknown. In this study, we examined the regulation of the Nur...
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| Published in: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642512/ https://ncbi.nlm.nih.gov/pubmed/29050237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19227 |
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