CFTR is a tumor suppressor gene in murine and human intestinal cancer

CFTR, the cystic fibrosis (CF) gene, encodes for the CFTR protein that plays an essential role in anion regulation and tissue homeostasis of various epithelia. In the gastrointestinal (GI) tract CFTR promotes chloride and bicarbonate secretion, playing an essential role in ion and acid–base homeosta...

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Publicado en:Oncogene
Autores principales: Than, BLN, Linnekamp, JF, Starr, TK, Largaespada, DA, Rod, A, Zhang, Y, Bruner, V, Abrahante, J, Schumann, A, Luczak, T, Niemczyk, A, O’Sullivan, MG, Medema, JP, Fijneman, RJA, Meijer, GA, Van den Broek, E, Hodges, CA, Scott, PM, Vermeulen, L, Cormier, RT
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940277/
https://ncbi.nlm.nih.gov/pubmed/26751771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.483
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