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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
Most mammalian cells do not divide indefinitely, owing to a process termed replicative senescence. In human cells, replicative senescence is caused by telomere shortening, but murine cells senesce despite having long stable telomeres(1). Here, we show that the phenotypes of senescent human fibroblas...
Shranjeno v:
| izdano v: | Nat Cell Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940195/ https://ncbi.nlm.nih.gov/pubmed/12855956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1024 |
| Oznake: |
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