טוען...
MYC Regulates the Anti-Tumor Immune Response through CD47 and PD-L1
The MYC oncogene codes for a transcription factor that is overexpressed in many human cancers. Here we show that MYC regulates the expression of two immune checkpoint proteins on the tumor cell surface, the innate immune regulator, CD47 (Cluster of Differentiation 47) and the adaptive immune checkpo...
שמור ב:
| הוצא לאור ב: | Science |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940030/ https://ncbi.nlm.nih.gov/pubmed/26966191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9935 |
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