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Development of Novel Anti-Cd20 Monoclonal Antibodies and Modulation in Cd20 Levels on Cell Surface: Looking to Improve Immunotherapy Response

Rituximab has been revolutionized and validated CD20 targeting monoclonal antibody. Although, it is widely used for lymphoma therapy and many patients have been benefited. However significant numbers of patients are refractory or developed resistance to current therapies due to low level of CD20 exp...

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Detalhes bibliográficos
Publicado no:J Cancer Sci Ther
Main Authors: Singh, Vijay, Gupta, Damodar, Almasan, Alexandru
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939752/
https://ncbi.nlm.nih.gov/pubmed/27413424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-5956.1000373
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