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Surface Levels of CD20 Determine Anti-CD20 Antibodies Mediated Cell Death In Vitro

BACKGROUND: The sensitivity of human Burkitt's lymphoma cells to rituximab (Rtx) and tositumomab (Tst) was assessed on cells expressing different levels of CD20 on surface. Cells that harbor low CD20 levels may resists against therapeutics response to CD20-specific antibodies. We postulated tha...

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Detalhes bibliográficos
Main Authors: Singh, Vijay, Gupta, Damodar, Arora, Rajesh, Tripathi, Rajendra Prashad, Almasan, Alexandru, Macklis, Roger M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217761/
https://ncbi.nlm.nih.gov/pubmed/25364827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111113
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