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Surface Levels of CD20 Determine Anti-CD20 Antibodies Mediated Cell Death In Vitro

BACKGROUND: The sensitivity of human Burkitt's lymphoma cells to rituximab (Rtx) and tositumomab (Tst) was assessed on cells expressing different levels of CD20 on surface. Cells that harbor low CD20 levels may resists against therapeutics response to CD20-specific antibodies. We postulated tha...

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Bibliografski detalji
Glavni autori: Singh, Vijay, Gupta, Damodar, Arora, Rajesh, Tripathi, Rajendra Prashad, Almasan, Alexandru, Macklis, Roger M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217761/
https://ncbi.nlm.nih.gov/pubmed/25364827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111113
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