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Anti-CD20 monoclonal antibodies: historical and future perspectives

Antibodies to CD20 have confirmed the hypothesis that monoclonal reagents can be given in vivo to alleviate human diseases. The targeting of CD20 on normal, malignant and auto-immune B-lymphocytes by rituximab has demonstrated substantial benefits for patients with a variety of B-cell lymphomas, as...

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Autors principals: Lim, Sean H., Beers, Stephen A., French, Ruth R., Johnson, Peter W.M., Glennie, Martin J., Cragg, Mark S.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805725/
https://ncbi.nlm.nih.gov/pubmed/19773256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.001628
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