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Anti-CD20 monoclonal antibodies: historical and future perspectives

Antibodies to CD20 have confirmed the hypothesis that monoclonal reagents can be given in vivo to alleviate human diseases. The targeting of CD20 on normal, malignant and auto-immune B-lymphocytes by rituximab has demonstrated substantial benefits for patients with a variety of B-cell lymphomas, as...

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Autori principali: Lim, Sean H., Beers, Stephen A., French, Ruth R., Johnson, Peter W.M., Glennie, Martin J., Cragg, Mark S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805725/
https://ncbi.nlm.nih.gov/pubmed/19773256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.001628
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