A Microfluidic Platform for Real-Time Detection and Quantification of Protein-Ligand Interactions

The key steps in cellular signaling and regulatory pathways rely on reversible noncovalent protein-ligand binding, yet the equilibrium parameters for such events remain challenging to characterize and quantify in solution. Here, we demonstrate a microfluidic platform for the detection of protein-lig...

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發表在:Biophys J
Main Authors: Herling, Therese W., O’Connell, David J., Bauer, Mikael C., Persson, Jonas, Weininger, Ulrich, Knowles, Tuomas P.J., Linse, Sara
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2016
主題:
Proteins
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939750/
https://ncbi.nlm.nih.gov/pubmed/27166804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.03.038
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