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Quantitative Proteomics Analysis of VEGF-Responsive Endothelial Protein S-Nitrosylation Using Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and LC-MS/MS

Adduction of a nitric oxide moiety (NO•) to cysteine(s), termed S-nitrosylation (SNO), is a novel mechanism for NO to regulate protein function directly. However, the endothelial SNO-protein network that is affected by endogenous and exogenous NO is obscure. This study was designed to develop a quan...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Zhang, Hong-Hai, Lechuga, Thomas J., Chen, Yuezhou, Yang, Yingying, Huang, Lan, Chen, Dong-Bao
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939742/
https://ncbi.nlm.nih.gov/pubmed/27075618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.116.139337
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