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Metabolic pathways promoting cancer cell survival and growth

Activation of oncogenes and loss of tumour suppressors promote metabolic reprogramming in cancer, resulting in enhanced nutrient uptake to supply energetic and biosynthetic pathways. However, nutrient limitations within solid tumours may require that malignant cells exhibit metabolic flexibility to...

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Publicado en:Nat Cell Biol
Main Authors: Boroughs, Lindsey K., DeBerardinis, Ralph J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939711/
https://ncbi.nlm.nih.gov/pubmed/25774832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3124
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