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Metabolic pathways promoting cancer cell survival and growth

Activation of oncogenes and loss of tumour suppressors promote metabolic reprogramming in cancer, resulting in enhanced nutrient uptake to supply energetic and biosynthetic pathways. However, nutrient limitations within solid tumours may require that malignant cells exhibit metabolic flexibility to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Cell Biol
Päätekijät: Boroughs, Lindsey K., DeBerardinis, Ralph J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939711/
https://ncbi.nlm.nih.gov/pubmed/25774832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3124
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