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Investigating Therapeutic Protein Structure with Diethylpyro-carbonate Labeling and Mass Spectrometry
Protein therapeutics are rapidly transforming the pharmaceutical industry. Unlike for small molecule therapeutics, current technologies are challenged to provide the rapid, high resolution analyses of protein higher order structures needed to ensure drug efficacy and safety. Consequently, significan...
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Publicado no: | Anal Chem |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939621/ https://ncbi.nlm.nih.gov/pubmed/26399599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b03180 |
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