Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring

Metabolic imaging of brain tumors using (13)C Magnetic Resonance Spectroscopy (MRS) of hyperpolarized [1-(13)C] pyruvate is a promising neuroimaging strategy which, after a decade of preclinical success in glioblastoma (GBM) models, is now entering clinical trials in multiple centers. Typically, the...

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Dettagli Bibliografici
Pubblicato in:Neuroimage Clin
Autori principali: Chaumeil, Myriam M., Radoul, Marina, Najac, Chloé, Eriksson, Pia, Viswanath, Pavithra, Blough, Michael D., Chesnelong, Charles, Luchman, H. Artee, Cairncross, J. Gregory, Ronen, Sabrina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939422/
https://ncbi.nlm.nih.gov/pubmed/27437179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2016.06.018
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