Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function

Epoxyeicosatrienoic acid (EET) contributes to browning of white adipose stem cells to ameliorate obesity/diabetes and insulin resistance. In the current study, we show that EET altered preadipocyte function, enhanced peroxisome proliferation-activated receptor γ coactivator α (PGC-1α) expression, an...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Waldman, Maayan, Bellner, Lars, Vanella, Luca, Schragenheim, Joseph, Sodhi, Komal, Singh, Shailendra P., Lin, Daohong, Lakhkar, Anand, Li, Jiangwei, Hochhauser, Edith, Arad, Michael, Darzynkiewicz, Zbigniew, Kappas, Atallah, Abraham, Nader G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939374/
https://ncbi.nlm.nih.gov/pubmed/27224420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0072
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