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Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation
The mitochondrial matrix is unique in that it must integrate folding and assembly of proteins derived from nuclear and mitochondrial genomes. In C. elegans, the mitochondrial unfolded protein response (UPR(mt)) senses matrix protein misfolding and induces a program of nuclear gene expression, includ...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939261/ https://ncbi.nlm.nih.gov/pubmed/27350246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18302 |
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