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Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation

The mitochondrial matrix is unique in that it must integrate folding and assembly of proteins derived from nuclear and mitochondrial genomes. In C. elegans, the mitochondrial unfolded protein response (UPR(mt)) senses matrix protein misfolding and induces a program of nuclear gene expression, includ...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Münch, Christian, Harper, J. Wade
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939261/
https://ncbi.nlm.nih.gov/pubmed/27350246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18302
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