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Curcumin and genistein additively potentiate G551D-CFTR
BACKGROUND: The G551D mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) is a common cause of cystic fibrosis (CF). G551D-CFTR is characterized by an extremely low open probability despite its normal trafficking to the plasma membrane. Numerous small molecules have been shown...
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| Publicado no: | J Cyst Fibros |
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| Principais autores: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939241/ https://ncbi.nlm.nih.gov/pubmed/21441077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2011.03.001 |
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