Curcumin and genistein additively potentiate G551D-CFTR

BACKGROUND: The G551D mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) is a common cause of cystic fibrosis (CF). G551D-CFTR is characterized by an extremely low open probability despite its normal trafficking to the plasma membrane. Numerous small molecules have been shown...

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Detalhes bibliográficos
Publicado no:J Cyst Fibros
Main Authors: Yu, Ying-Chun, Miki, Haruna, Nakamura, Yumi, Hanyuda, Akiko, Matsuzaki, Yohei, Abe, Yoichiro, Yasui, Masato, Tanaka, Kazuhiko, Hwang, Tzyh-Chang, Bompadre, Silvia G., Sohma, Yoshiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939241/
https://ncbi.nlm.nih.gov/pubmed/21441077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2011.03.001
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