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Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats
Xanthine oxidase (XO) is an enzyme responsible for the production of uric acid. XO produces considerable amount of oxidative stress throughout the body. To date, however, its pathophysiologic role in hypertension and endothelial dysfunction still remains controversial. To explore the possible involv...
Zapisane w:
| Wydane w: | Naunyn Schmiedebergs Arch Pharmacol |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer Berlin Heidelberg
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939152/ https://ncbi.nlm.nih.gov/pubmed/27198514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-016-1239-1 |
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