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Amyotrophic Lateral Sclerosis Risk for Spinocerebellar Ataxia Type 2 ATXN2 CAG Repeat Alleles: A Meta-analysis

IMPORTANCE: Repeats of CAG in the ataxin 2 gene (ATXN2) in the long-normal range (sometimes referred to as intermediate) have been identified as modifiers of amyotrophic lateral sclerosis (ALS) risk. Prior studies have used thresholding considering various cutoffs for ATXN2 repeat length. OBJECTIVE:...

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Udgivet i:JAMA Neurol
Main Authors: Neuenschwander, Annalese G., Thai, Khanh K., Figueroa, Karla P., Pulst, Stefan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939089/
https://ncbi.nlm.nih.gov/pubmed/25285812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.2082
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