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The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway

Mycobacterium smegmatis is a bacterium that is naturally devoid of known postreplicative DNA mismatch repair (MMR) homologs, mutS and mutL, providing an opportunity to investigate how the mutation rate and spectrum has evolved in the absence of a highly conserved primary repair pathway. Mutation acc...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Kucukyildirim, Sibel, Long, Hongan, Sung, Way, Miller, Samuel F., Doak, Thomas G., Lynch, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938668/
https://ncbi.nlm.nih.gov/pubmed/27194804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.030130
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