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The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway

Mycobacterium smegmatis is a bacterium that is naturally devoid of known postreplicative DNA mismatch repair (MMR) homologs, mutS and mutL, providing an opportunity to investigate how the mutation rate and spectrum has evolved in the absence of a highly conserved primary repair pathway. Mutation acc...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Kucukyildirim, Sibel, Long, Hongan, Sung, Way, Miller, Samuel F., Doak, Thomas G., Lynch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938668/
https://ncbi.nlm.nih.gov/pubmed/27194804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.030130
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