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The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway

Mycobacterium smegmatis is a bacterium that is naturally devoid of known postreplicative DNA mismatch repair (MMR) homologs, mutS and mutL, providing an opportunity to investigate how the mutation rate and spectrum has evolved in the absence of a highly conserved primary repair pathway. Mutation acc...

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Kucukyildirim, Sibel, Long, Hongan, Sung, Way, Miller, Samuel F., Doak, Thomas G., Lynch, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938668/
https://ncbi.nlm.nih.gov/pubmed/27194804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.030130
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