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A Novel Missense Mutation of GATA4 in a Chinese Family with Congenital Heart Disease

BACKGROUND: Congenital heart disease (CHD) is the most prevalent type of birth defect in human, with high morbidity in infant. Several genes essential for heart development have been identified. GATA4 is a pivotal transcription factor that can regulate the cardiac development. Many GATA4 mutations h...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Xiaoqing, Wang, Jian, Wang, Bo, Chen, Sun, Fu, Qihua, Sun, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938561/
https://ncbi.nlm.nih.gov/pubmed/27391137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158904
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