Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors

There exist two isoforms of cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) in pig populations that differ in a single amino acid (Met139Leu). The isoenzymes have different kinetic properties, affecting more strongly the K(m) and V(max) of nucleotides. They are associated to different phenotyp...

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Publicat a:PLoS One
Autors principals: Hidalgo, Jorge, Latorre, Pedro, Carrodeguas, José Alberto, Velázquez-Campoy, Adrián, Sancho, Javier, López-Buesa, Pascual
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938538/
https://ncbi.nlm.nih.gov/pubmed/27391465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159002
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